[ by Melanie Gretchen ] Goldman Sachs is moving up the ladder as it cuts out the positions of managing directors whose remuneration includes a base pay of $500,000 and an annual bonus that can run into the millions.  All told, the New York firm cut some 50 people last week, according to people briefed on the matter but not authorized to speak on the record. Hard Times. Admit Europe's mounting debt problems and new regulations, the Wall Street firm continues its paring, following layoffs of 8.5% of its work force, or 3,000, in the last year.  In noncompensation expenses, the firm has cut more than $1.4 billion over the last year or so, admit second-quarter earnings estimates down for the banks. Not everyone has been so unlucky.  Strategic or budgetary reasons have appointed new division managers (room was made by more staffing cuts). In turn, Morgan Stanley made cuts of 2,935 during the 12 months ending 3/31/12, 4.7% of its work force.  Credit Suisse filed a notice with the New York Department of Labor, detailing plans to lay off 109 people in the state before 5/1/12. For further details, go to [Dealbook, 6/4/12].